Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27437443 | 0.90 | GCK (0.55) | LMNAMEN1KMT2AGAAMAPT | |
| SCHEMBL8155617 | 0.88 | LMNA (0.46) | GABRA5LMNAMEN1KMT2AGAA | |
| SCHEMBL8162400 | 0.84 | SMN1; SMN2 (0.50) | GABRA5MEN1KMT2AGAAMAPT | |
| SCHEMBL20722658 | 0.84 | CA1 (0.62) | GABRA5L3MBTL1KDM4EHDAC3HDAC1 | |
| SCHEMBL6255906 | 0.84 | GABRA5 (0.53) | GABRA5L3MBTL1KDM4EATMHDAC1 | |
| SCHEMBL8163768 | 0.81 | GABRA5 (0.52) | GABRA5LMNAMEN1KMT2AGAA | |
| SCHEMBL8325607 | 0.81 | PTGER1 (0.52) | LMNAKMT2AMAPTL3MBTL1HPGD | |
| SCHEMBL4829706 | 0.80 | ATM (0.64) | GAAKDM4EATMHDAC3HDAC1 | |
| SCHEMBL7348393 | 0.80 | SGMS2 (0.65) | MEN1KMT2AGAAKDM4ETP53 | |
| SCHEMBL8155926 | 0.79 | CCR5 (0.50) | LMNAALDH1A1RAB9APTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |