Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062969 | 0.80 | ALDH1A1 (0.39) | THRBALDH1A1MAPTHPGDTSHR | |
| Methacrylic Acid SCHEMBL7544463 | 0.80 | THRB (0.50) | THRBALDH1A1MAPTHPGDTSHR | |
| SCHEMBL42562 | 0.77 | THRB (0.58) | THRBALDH1A1MAPTHPGDTSHR | |
| SCHEMBL8020679 | 0.75 | THRB (0.41) | THRBALDH1A1MAPTHPGDTSHR | |
| SCHEMBL2392778 | 0.73 | MTNR1A (0.50) | THRBALDH1A1MAPTHPGDTSHR | |
| SCHEMBL268177 | 0.73 | THRB (0.40) | THRBALDH1A1TSHRKDM4E | |
| SCHEMBL7873904 | 0.70 | THRB (0.40) | THRBALDH1A1TSHRKDM4E | |
| SCHEMBL29311777 | 0.70 | ALDH1A1 (0.50) | THRBALDH1A1MAPTHPGDTSHR | |
| SCHEMBL10033080 | 0.70 | ALDH1A1 (0.58) | THRBALDH1A1TSHRRECQLSMN1; SMN2 | |
| SCHEMBL10033082 | 0.70 | ALDH1A1 (0.58) | THRBALDH1A1TSHRRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000034804-A1 | HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-06-15 | — | — | WO | disclosed |