Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026798 | 0.95 | ACE (0.39) | ACE | |
| SCHEMBL8023094 | 0.88 | MMP1 (0.43) | ACE | |
| SCHEMBL8165378 | 0.84 | ACE (0.47) | ACE | |
| SCHEMBL8167144 | 0.84 | ACE (0.47) | ACE | |
| SCHEMBL8022583 | 0.81 | FFAR1 (0.46) | — | |
| SCHEMBL8023170 | 0.81 | FFAR1 (0.42) | ACE | |
| SCHEMBL8010235 | 0.80 | MMP12 (0.47) | — | |
| SCHEMBL8161868 | 0.79 | ACE (0.41) | ACE | |
| SCHEMBL8024511 | 0.79 | TSHR (0.47) | — | |
| SCHEMBL8159707 | 0.77 | ACE (0.50) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156774-A | Beta-thiopropionyl-amino acid derivatives and their use as beta-lactamase inhibitors | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-05 | — | — | US | claimed |
| US-6156774-A | Beta-thiopropionyl-amino acid derivatives and their use as beta-lactamase inhibitors | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-05 | — | — | US | disclosed |