Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL52219 | 0.90 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPK1TSHRCSNK1D | |
| SCHEMBL12304981 | 0.86 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL419807 | 0.84 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2TSHR | |
| SCHEMBL27358219 | 0.84 | TDP1 (0.49) | ALDH1A1L3MBTL1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL16672447 | 0.83 | LMNA (0.50) | ALDH1A1L3MBTL1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL21801168 | 0.82 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2TSHR | |
| SCHEMBL23684580 | 0.81 | PAM (0.65) | ALDH1A1L3MBTL1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL27338787 | 0.81 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPK1RAB9ASMN1; SMN2 | |
| Ether SCHEMBL954914 | 0.81 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL24722404 | 0.81 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404222-B2 | Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution | NEKTAR THERAPEUTICS (US) | 2013-03-26 | — | — | US | disclosed |
| US-20120071627-A1 | Soluble, Degradable Poly(ethylene glycol) Derivatives for Controllable Release of Bound Molecules into Solution | NEKTAR THERAPEUTICS (US) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071627-A1 | Soluble, Degradable Poly(ethylene glycol) Derivatives for Controllable Release of Bound Molecules into Solution | IDE, EGFR, IDUA | ALDH1A1 1709/4885L3MBTL1 3666/4885MAPK1 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.