Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | F13A1 | P00488 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ESRRG | P62508 | 4/20 | 0.56 |
| ▸ | ESRRB | O95718 | 3/20 | 0.56 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28747980 | 0.87 | KDM4E (0.65) | KDM4EF13A1GAAGFERNPC1 | |
| SCHEMBL14370357 | 0.86 | KDM4E (0.69) | KDM4EF13A1GAAGFERNPC1 | |
| SCHEMBL1329289 | 0.83 | HDAC2 (0.60) | GAANPC1RAB9ASMN1; SMN2PLAAT5 | |
| SCHEMBL2191045 | 0.83 | KDM4E (0.65) | KDM4EF13A1GAAGFERNPC1 | |
| SCHEMBL4161209 | 0.83 | ESRRB (0.77) | KDM4EF13A1GAAGFERNPC1 | |
| SCHEMBL2379821 | 0.83 | KDM4E (0.65) | KDM4EF13A1GAAGFERNPC1 | |
| SCHEMBL23700596 | 0.81 | KDM4E (0.62) | KDM4EF13A1GAAGFERNPC1 | |
| SCHEMBL6424890 | 0.81 | KDM4E (0.62) | KDM4EF13A1GAAGFERNPC1 | |
| SCHEMBL6425050 | 0.81 | KDM4E (0.62) | KDM4EF13A1GAAGFERNPC1 | |
| SCHEMBL21377225 | 0.81 | KDM4E (0.62) | KDM4EF13A1GAAGFERNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000077520-A1 | LABELLING OF PEPTIDES AND PROTEINS | PROTEOSYS AG (DE) | 2000-12-21 | — | — | WO | claimed |
| EP-1059531-A1 | Labelling of peptides and proteins | Nordheim, Alfred, Prof. Dr. (DE) | 2000-12-13 | — | — | EP | claimed |
| CN-117980737-A | Identification method of active sulfur | 公立大学法人大阪 | 2024-05-03 | — | — | CN | disclosed |
| EP-4343325-A1 | BIOMARKER FOR INFECTIOUS DISEASE | Tohoku University (JP) | 2024-03-27 | — | — | EP | disclosed |
| US-20240084342-A1 | CYSTEINE POLYSULFIDATION AND MITOCHONDRIAL BIOENERGETICS REGULATED BY CYSTEINYL-tRNA SYNTHETASE | TOHOKU UNIVERSITY (JP) | 2024-03-14 | — | — | US | disclosed |
| US-20240085401-A1 | BIOMARKER FOR INFECTIOUS DISEASE | Bio-Xcelerator, Inc. (JP) | 2024-03-14 | — | — | US | disclosed |
| CN-117586160-A | Sulfur-containing prodrug compound and medical application thereof | 中国药科大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-117589892-A | Method for quantitative determination of active sulfur | 株式会社岛津制作所 | 2024-02-23 | — | — | CN | disclosed |
| US-20240053306-A1 | QUANTITATIVE DETERMINATION METHOD FOR REACTIVE SULFUR | SHIMADZU CORPORATION (JP) | 2024-02-15 | — | — | US | disclosed |
| US-20230242479-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | THE JOHNS HOPKINS UNIVERSTY | 2023-08-03 | — | — | US | disclosed |
| US-20230147021-A1 | POLYSULFIDE STABILIZATION | UNIVERSITY PUBLIC CORPORATION OSAKA (JP) | 2023-05-11 | — | — | US | disclosed |
| US-11584712-B2 | Alkylamine-substituted perthiocarbamates as dual precursors to hydropersulfide and carbonyl sulfide | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
| EP-4112597-A1 | STABILIZATION OF POLYSULFIDE | University Public Corporation Osaka (JP) | 2023-01-04 | — | — | EP | disclosed |
| CN-115515928-A | Stabilization of polysulfides | 公立大学法人大阪 | 2022-12-23 | — | — | CN | disclosed |
| US-20220127584-A1 | Reactive persulfides mediate sulfur respiration in mitochondria via sulfide:quinone oxidoreductase | TOHOKU UNIVERSITY (JP) | 2022-04-28 | — | — | US | disclosed |
| US-20210403963-A1 | CYSTEINE POLYSULFIDATION AND MITOCHONDRIAL BIOENERGETICS REGULATED BY CYSTEINYL-tRNA SYNTHETASE | TOHOKU UNIVERSITY (JP) | 2021-12-30 | — | — | US | disclosed |
| US-20210238134-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | NATIONAL SCIENCE FOUNDATION | 2021-08-05 | — | — | US | disclosed |
| US-20200270655-A1 | CYSTEINE POLYSULFIDATION AND MITOCHONDRIAL BIOENERGETICS REGULATED BY CYSTEINYL-tRNA SYNTHETASE | AKAIKE, TAKAAKI (JP) | 2020-08-27 | — | — | US | disclosed |
| WO-2000077520-A1 | LABELLING OF PEPTIDES AND PROTEINS | PROTEOSYS AG (DE) | 2000-12-21 | — | — | WO | disclosed |
| EP-1059531-A1 | Labelling of peptides and proteins | Nordheim, Alfred, Prof. Dr. (DE) | 2000-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230147021-A1 | POLYSULFIDE STABILIZATION | YWHAZ, YWHAH, PTPN21 | KDM4E 607/4885F13A1 1050/4885GAA 456/4885 |
| US-20210238134-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | CTH, DOHH, HAGH | KDM4E 4672/4885F13A1 2960/4885GAA 3776/4885 |
| US-20230242479-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | CTH, DOHH, HAGH | KDM4E 4672/4885F13A1 2960/4885GAA 3776/4885 |
| US-11584712-B2 | Alkylamine-substituted perthiocarbamates as dual precursors to hydropersulfide and carbonyl sulfide | CTH, DOHH, HAGH | KDM4E 4672/4885F13A1 2960/4885GAA 3776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.