Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 2/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034187 | 0.93 | HTR1A (0.44) | ALDH1A1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL8046481 | 0.89 | ALDH1A1 (0.44) | POLBHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL8043688 | 0.88 | HTR1A (0.46) | HPGDALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL8033682 | 0.88 | RAB9A (0.45) | HPGDALDH1A1RAB9ANPC1HTR1A | |
| SCHEMBL8044049 | 0.88 | HTR1A (0.54) | RAB9ANPC1MAPTKMT2AHTR1A | |
| SCHEMBL8043865 | 0.85 | RAB9A (0.42) | ALDH1A1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL8041849 | 0.84 | RAB9A (0.38) | POLBHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL8720492 | 0.82 | RAB9A (0.41) | HPGDALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL8048583 | 0.82 | ALDH1A1 (0.45) | HPGDALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL8043192 | 0.81 | ALDH1A1 (0.35) | POLBHPGDALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |