Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044646 | 0.93 | ALDH1A1 (0.52) | ALDH1A1POLBMEN1KMT2ACYP1A2 | |
| SCHEMBL8033580 | 0.89 | POLB (0.44) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL8043207 | 0.89 | MAPT (0.44) | ALDH1A1POLBMEN1KMT2ACYP1A2 | |
| SCHEMBL8032462 | 0.88 | CYP2C19 (0.39) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL8042704 | 0.88 | DCUN1D1 (0.44) | ALDH1A1POLBMEN1KMT2ACYP1A2 | |
| SCHEMBL8720492 | 0.85 | RAB9A (0.41) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL8051108 | 0.85 | KMT2A (0.38) | ALDH1A1POLBMEN1KMT2ACYP1A2 | |
| SCHEMBL8042146 | 0.83 | KDM4E (0.42) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL8050040 | 0.82 | HTT (0.51) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL8034187 | 0.81 | HTR1A (0.44) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |