Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044430 | 0.94 | CTSS (0.34) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8032734 | 0.89 | ALDH1A1 (0.37) | ALDH1A1MAPTUSP2HTTGAA | |
| SCHEMBL8047810 | 0.89 | CYP2C9 (0.37) | ALDH1A1MAPTUSP2LMNAHTT | |
| SCHEMBL8043614 | 0.89 | DCUN1D1 (0.41) | DCUN1D1UBE2M | |
| SCHEMBL8033576 | 0.86 | CXCR3 (0.31) | HTTPAX8PIP4K2CDCUN1D1UBE2M | |
| SCHEMBL8046511 | 0.83 | HTT (0.45) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8037022 | 0.83 | HTT (0.38) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8050186 | 0.82 | ATP4A (0.35) | ALDH1A1MAPTKMT2ACTSSCTSK | |
| SCHEMBL8033580 | 0.81 | POLB (0.44) | ALDH1A1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL8048771 | 0.81 | MAPT (0.37) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |