Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041886 | 0.92 | SMN1; SMN2 (0.45) | ALDH1A1L3MBTL1SMN1; SMN2TSHRMAPT | |
| SCHEMBL8043200 | 0.92 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1SMN1; SMN2TSHRMAPT | |
| SCHEMBL8048723 | 0.89 | VCP (0.48) | ALDH1A1L3MBTL1SMN1; SMN2TSHRMAPT | |
| SCHEMBL8043675 | 0.87 | KIT (0.39) | ALDH1A1L3MBTL1KDM4EHTTPOLB | |
| SCHEMBL8043905 | 0.85 | KDM4E (0.37) | ALDH1A1SMN1; SMN2TSHRMAPTNPSR1 | |
| SCHEMBL8045341 | 0.84 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1SMN1; SMN2TSHRMAPT | |
| SCHEMBL8046275 | 0.84 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1SMN1; SMN2TSHRMAPT | |
| SCHEMBL8050838 | 0.84 | KDM4E (0.36) | ALDH1A1SMN1; SMN2TSHRMAPTKDM4E | |
| SCHEMBL8044497 | 0.83 | HTT (0.33) | ALDH1A1MAPTKDM4EARHTT | |
| SCHEMBL8037043 | 0.83 | SMN1; SMN2 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |