Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043580 | 0.86 | HTT (0.43) | HTTALDH1A1CYP2C19 | |
| SCHEMBL8033927 | 0.84 | NPSR1 (0.40) | HTTALDH1A1CYP2C19 | |
| SCHEMBL8043236 | 0.83 | UBE2M (0.35) | HTTALDH1A1TP53 | |
| SCHEMBL8033964 | 0.81 | SMN1; SMN2 (0.39) | HTTALDH1A1TP53CYP2C19 | |
| SCHEMBL8047183 | 0.79 | — | — | |
| SCHEMBL8033786 | 0.79 | MAPT (0.39) | ALDH1A1 | |
| SCHEMBL8051249 | 0.79 | RAB9A (0.35) | HTTALDH1A1 | |
| SCHEMBL8047418 | 0.78 | KMT2A (0.38) | ALDH1A1CYP2C19 | |
| SCHEMBL8032986 | 0.77 | RXRA (0.34) | HTTALDH1A1TP53CYP2C19 | |
| SCHEMBL8042294 | 0.77 | ALDH1A1 (0.38) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |