Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044527 | 0.93 | RAB9A (0.35) | LOXL2TOP2A | |
| SCHEMBL8045845 | 0.90 | TRPM8 (0.32) | LOXL2 | |
| SCHEMBL8032788 | 0.84 | PTGS2 (0.33) | LOXL2 | |
| SCHEMBL8034005 | 0.83 | MEN1 (0.34) | RECQL | |
| SCHEMBL8045587 | 0.83 | — | — | |
| SCHEMBL8048224 | 0.81 | RAB9A (0.39) | LOXL2 | |
| SCHEMBL8044148 | 0.78 | — | — | |
| SCHEMBL8044693 | 0.78 | — | — | |
| SCHEMBL8045984 | 0.77 | MAPK8 (0.51) | — | |
| SCHEMBL8045938 | 0.77 | HSD17B10 (0.40) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |