Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SCD | O00767 | 6/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034002 | 0.83 | LOXL2 (0.32) | RECQL | |
| SCHEMBL8048224 | 0.82 | RAB9A (0.39) | LMNAALDH1A1KDM4EHTT | |
| SCHEMBL8044527 | 0.81 | RAB9A (0.35) | MEN1KMT2ALMNAALDH1A1HTT | |
| SCHEMBL8046142 | 0.81 | RXRA (0.38) | MEN1KMT2ARECQLSCD | |
| SCHEMBL8037025 | 0.81 | MEN1 (0.37) | MEN1KMT2ASCD | |
| SCHEMBL8032788 | 0.80 | PTGS2 (0.33) | KMT2AKDM4E | |
| SCHEMBL8045587 | 0.79 | — | — | |
| SCHEMBL8050401 | 0.78 | KMT2A (0.36) | KMT2ALMNATP53ALDH1A1HTT | |
| SCHEMBL8044469 | 0.77 | MAPK8 (0.46) | MEN1KMT2ALMNAALDH1A1HTT | |
| SCHEMBL8044693 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |