Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034002 | 0.93 | LOXL2 (0.32) | TOP2ALOXL2 | |
| SCHEMBL8045845 | 0.88 | TRPM8 (0.32) | LOXL2 | |
| SCHEMBL8032788 | 0.82 | PTGS2 (0.33) | KMT2ALOXL2 | |
| SCHEMBL8034005 | 0.81 | MEN1 (0.34) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL8045587 | 0.81 | — | — | |
| SCHEMBL8046313 | 0.81 | ALDH1A1 (0.35) | RAB9AALDH1A1KMT2AMAPTF2 | |
| SCHEMBL8048224 | 0.80 | RAB9A (0.39) | RAB9AALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL8044846 | 0.79 | RAB9A (0.42) | RAB9AALDH1A1KMT2AMAPTF2 | |
| SCHEMBL8032365 | 0.78 | MAPK8 (0.49) | RAB9AALDH1A1KMT2AMAPTF2 | |
| SCHEMBL8033250 | 0.78 | HTT (0.41) | ALDH1A1KMT2AMAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |