Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 3/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051771 | 0.86 | ALOX5 (0.36) | LTA4HALOX5MPLMYCWDR5 | |
| SCHEMBL8042665 | 0.85 | MAPT (0.41) | ALOX5MPLPKMMAPK1MAPT | |
| SCHEMBL8043997 | 0.83 | MAPT (0.35) | LTA4HALOX5MYCWDR5MAPT | |
| SCHEMBL8046557 | 0.82 | CTSS (0.35) | LTA4HALOX5MAPTEIF4EF2RL3 | |
| SCHEMBL8033655 | 0.82 | EIF4E (0.34) | LTA4HALOX5RORBRORCMAPT | |
| SCHEMBL8044824 | 0.82 | MAPT (0.34) | ALOX5MAPTEIF4EF2RL3 | |
| SCHEMBL8052850 | 0.81 | KMT2A (0.43) | ALOX5EIF4EADORA2AADORA1 | |
| SCHEMBL8048125 | 0.80 | CTSK (0.41) | LTA4HALOX5MAPTEIF4EF2RL3 | |
| SCHEMBL8044775 | 0.80 | EIF4E (0.33) | LTA4HALOX5MAPTEIF4EF2RL3 | |
| SCHEMBL8046645 | 0.80 | ALDH1A1 (0.39) | ALOX5RORBRORCEIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |