Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23691461 | 0.87 | POLB (0.41) | POLBGABRA1GABRB2MAPTKDM4E | |
| SCHEMBL12257695 | 0.85 | POLB (0.39) | POLBGABRA1GABRB2MAPTKDM4E | |
| SCHEMBL3186915 | 0.83 | HTT (0.40) | POLBGABRA1GABRB2MAPTKDM4E | |
| SCHEMBL3178396 | 0.83 | NOS3 (0.54) | POLBGABRA1GABRB2MAPTKDM4E | |
| SCHEMBL26860342 | 0.83 | POLB (0.38) | POLBGABRA1GABRB2MAPTKDM4E | |
| SCHEMBL11955165 | 0.83 | POLB (0.38) | POLBGABRA1GABRB2MAPTKDM4E | |
| SCHEMBL24277974 | 0.81 | POLB (0.37) | POLBGABRA1GABRB2MAPTKDM4E | |
| SCHEMBL25456469 | 0.79 | NOS3 (0.39) | POLBGABRA1GABRB2MAPTKDM4E | |
| SCHEMBL18051319 | 0.79 | HSP90AA1 (0.52) | POLBGABRA1GABRB2MAPTKDM4E | |
| SCHEMBL13172167 | 0.79 | CYP1A2 (0.39) | POLBGABRA1GABRB2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136757-A | Synthesis method of 6-hydroxy-2-azaspiro [3.3] heptane compounds | 浙江中科创越药业有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-120136757-A | Synthesis method of 6-hydroxy-2-azaspiro [3.3] heptane compounds | 浙江中科创越药业有限公司 | 2025-06-13 | — | — | CN | disclosed |
| US-12035618-B2 | Electroluminescent devices | UNIVERSAL DISPLAY CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | ASCENEURON SA (CH) | 2024-06-25 | — | — | US | disclosed |
| US-11912685-B2 | Biphenyl diaryl pyrimidine derivative with aromatic heterocyclic structure | FUDAN UNIVERSITY (CN) | 2024-02-27 | — | — | US | disclosed |
| US-11912685-B2 | Biphenyl diaryl pyrimidine derivative with aromatic heterocyclic structure | FUDAN UNIVERSITY (CN) | 2024-02-27 | — | — | US | disclosed |
| US-11832510-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-28 | — | — | US | disclosed |
| US-11832510-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-28 | — | — | US | disclosed |
| US-20230355617-A1 | SMALL MOLECULE INHIBITORS OF LEMUR TYROSINE KINASE 3 | THE UNIVERSITY OF SUSSEX (GB) | 2023-11-09 | — | — | US | disclosed |
| US-20230348508-A1 | METAL COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME, AND CONSUMER PRODUCT | BEIJING BAYI SPACE LIQUID CRYSTAL TECHNOLOGY CO. LTD. (CN) | 2023-11-02 | — | — | US | disclosed |
| US-20120172217-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | disclosed |
| EP-2461687-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
| WO-2011017504-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
| US-20100234364-A1 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CHEMOCENTRYX, INC. | 2010-09-16 | — | — | US | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
| US-7312209-B2 | Acridone inhibitors of IMPDH enzyme | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312209-B2 | Acridone inhibitors of IMPDH enzyme | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DDT, ACHE, NANP | POLB 4778/4885GABRA1 1828/4885GABRB2 2005/4885 |
| US-11832510-B2 | Organic electroluminescent materials and devices | OSBP, OCIAD2, OCIAD1 | POLB 1250/4885GABRA1 4296/4885GABRB2 3585/4885 |
| US-12035618-B2 | Electroluminescent devices | ELAVL1, ELAVL3, JUND | POLB 1033/4885GABRA1 3618/4885GABRB2 3079/4885 |
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | PREP, GAA, DNPEP | POLB 338/4885GABRA1 4399/4885GABRB2 3311/4885 |
| US-20230355617-A1 | SMALL MOLECULE INHIBITORS OF LEMUR TYROSINE KINASE 3 | LMTK3, LMTK2, LIMK1 | POLB 4268/4885GABRA1 3556/4885GABRB2 2811/4885 |
| US-11912685-B2 | Biphenyl diaryl pyrimidine derivative with aromatic heterocyclic structure | DPYD, TYMP, DHODH | POLB 1306/4885GABRA1 1926/4885GABRB2 2371/4885 |
| US-20100234364-A1 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CCR2, CCR9, CCR1 | POLB 4104/4885GABRA1 848/4885GABRB2 978/4885 |
| US-20120172217-A1 | PESTICIDAL COMPOSITIONS | DDT, AADAC, ACHE | POLB 4737/4885GABRA1 2853/4885GABRB2 1517/4885 |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | POLB 4172/4885GABRA1 2017/4885GABRB2 1378/4885 |
| US-20230348508-A1 | METAL COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME, AND CONSUMER PRODUCT | TRPM5, TRPM6, TRPM2 | POLB 3216/4885GABRA1 3933/4885GABRB2 4086/4885 |
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | POLB 3355/4885GABRA1 127/4885GABRB2 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.