Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031648 | 0.90 | SMN1; SMN2 (0.52) | APPNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8038345 | 0.82 | HPGD (0.52) | APPNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8031650 | 0.81 | MEN1 (0.46) | APPNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8034163 | 0.81 | CTSV (0.47) | APPNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8022341 | 0.81 | MEN1 (0.50) | APPNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8022338 | 0.79 | TRPM8 (0.46) | APPNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8035938 | 0.79 | SRD5A1 (0.47) | APPNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8034161 | 0.79 | APP (0.47) | APPNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8039013 | 0.79 | ALDH1A1 (0.41) | RAB9AMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL8037071 | 0.78 | MEN1 (0.47) | APPNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |