Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.41 |
| ▸ | GRM8 | O00222 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8025542 | 1.00 | ALDH5A1 (0.42) | ALDH5A1ABATGRM4GRM8ALDH1A1 | |
| Lysine SCHEMBL8037517 | 0.89 | GRM4 (0.43) | ALDH5A1ABATGRM4GRM8XDH | |
| Lysine SCHEMBL8037518 | 0.89 | GRM4 (0.43) | ALDH5A1ABATGRM4GRM8XDH | |
| Cyclohexylamine SCHEMBL7798582 | 0.89 | ALDH5A1 (0.46) | ALDH5A1ABATGRM4GRM8ALDH1A1 | |
| Cyclohexylamine SCHEMBL7801795 | 0.88 | ALDH5A1 (0.54) | ALDH5A1ABATALDH1A1MAPTKDM4E | |
| Cyclohexylamine SCHEMBL8035231 | 0.87 | VCAM1 (0.53) | ALDH5A1ABATGRM4GRM8ALDH1A1 | |
| Cyclohexylamine SCHEMBL8035226 | 0.87 | VCAM1 (0.53) | ALDH5A1ABATGRM4GRM8ALDH1A1 | |
| Cyclohexylamine SCHEMBL8035135 | 0.85 | GRIK1 (0.46) | GRM4GRM8ALDH1A1MAPTKDM4E | |
| Cyclohexylamine SCHEMBL8035138 | 0.85 | GRIK1 (0.46) | GRM4GRM8ALDH1A1MAPTKDM4E | |
| 3-Nitrobenzaldehyde SCHEMBL8039154 | 0.82 | KMO (0.46) | GRM4GRM8ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |