Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045896 | 0.87 | CCR1 (0.41) | L3MBTL1CYP4F2CYP4A11BRD4ALDH1A1 | |
| SCHEMBL8046467 | 0.87 | CCR1 (0.41) | L3MBTL1CYP4F2CYP4A11BRD4ALDH1A1 | |
| SCHEMBL8046393 | 0.87 | L3MBTL1 (0.44) | POLBL3MBTL1CYP4F2CYP4A11BRD4 | |
| SCHEMBL8046383 | 0.86 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2KCNA3 | |
| SCHEMBL8035567 | 0.84 | CA12 (0.40) | POLBCYP4F2CYP4A11ALDH1A1KCNA3 | |
| SCHEMBL8053206 | 0.83 | FAAH (0.44) | CYP4F2CYP4A11ALDH1A1KCNA3OPRM1 | |
| SCHEMBL8044856 | 0.83 | OPRM1 (0.48) | POLBCYP4F2CYP4A11ALDH1A1SMN1; SMN2 | |
| SCHEMBL8049892 | 0.83 | OPRM1 (0.48) | POLBCYP4F2CYP4A11ALDH1A1SMN1; SMN2 | |
| SCHEMBL8052628 | 0.83 | HDAC1 (0.44) | NR1H4 | |
| SCHEMBL8046405 | 0.82 | SMN1; SMN2 (0.51) | L3MBTL1BRD4SMN1; SMN2FFAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |