Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045896 | 1.00 | CCR1 (0.41) | CCR1ALOX15L3MBTL1TBXAS1MAPT | |
| SCHEMBL8052660 | 0.91 | PPARG (0.43) | CCR1L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL8046393 | 0.90 | L3MBTL1 (0.44) | L3MBTL1MAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL8046383 | 0.89 | CYP4F2 (0.40) | ALOX15TBXAS1ALDH1A1KDM4EHPGD | |
| SCHEMBL8035567 | 0.88 | CA12 (0.40) | ALOX15ALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL8044912 | 0.87 | POLB (0.36) | ALOX15L3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL8053206 | 0.86 | FAAH (0.44) | CCR1ALOX15MAPTALDH1A1NPSR1 | |
| SCHEMBL8049892 | 0.86 | OPRM1 (0.48) | CCR1TBXAS1ALDH1A1SMN1; SMN2CYP4F2 | |
| SCHEMBL8044856 | 0.86 | OPRM1 (0.48) | CCR1TBXAS1ALDH1A1SMN1; SMN2CYP4F2 | |
| SCHEMBL7824585 | 0.85 | OPRM1 (0.46) | CCR1ALOX15L3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |