Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 4/20 | 0.32 |
| ▸ | LIG1 | P18858 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | VNN1 | O95497 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047273 | 0.83 | IL2 (0.35) | ACHE | |
| SCHEMBL3669504 | 0.81 | LSS (0.46) | EZH2LMNAARACHEKMT2A | |
| SCHEMBL3669501 | 0.81 | LSS (0.46) | EZH2LMNAARACHEKMT2A | |
| SCHEMBL8035846 | 0.80 | LSS (0.43) | LMNAACHEKMT2AMEN1 | |
| SCHEMBL7767787 | 0.75 | LSS (0.40) | LMNAKMT2AMEN1 | |
| SCHEMBL7769001 | 0.74 | THRA (0.39) | LMNA | |
| SCHEMBL7772085 | 0.73 | KDM4E (0.34) | LMNAPOLB | |
| SCHEMBL7764172 | 0.73 | KDM4E (0.33) | LMNAKMT2AMEN1 | |
| SCHEMBL7772100 | 0.73 | KDM4E (0.33) | LMNAPOLB | |
| SCHEMBL8047705 | 0.72 | PPARD (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636367-B1 | Use of phenylalkylamines for producing cholesterol lowering agents | HOFFMANN LA ROCHE (CH) | 2000-03-29 | — | — | EP | claimed |