Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035102 | 0.89 | POLB (0.50) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8039106 | 0.77 | POLB (0.45) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8034167 | 0.72 | APP (0.51) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL8031648 | 0.70 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL3225808 | 0.69 | POLB (0.59) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8039013 | 0.69 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL1255362 | 0.68 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8041234 | 0.68 | POLB (0.47) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL1787071 | 0.67 | TSHR (0.57) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL3221137 | 0.66 | LGMN (0.61) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |