Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036992 | 0.89 | GLA (0.50) | POLBMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL8039013 | 0.81 | ALDH1A1 (0.41) | POLBALDH1A1TSHRLMNAKMT2A | |
| SCHEMBL8039106 | 0.79 | POLB (0.45) | POLBMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL8041234 | 0.79 | POLB (0.47) | POLBMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL3225808 | 0.72 | POLB (0.59) | POLBMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL8025474 | 0.71 | TSHR (0.39) | MAPTKDM4ETSHRLMNAKMT2A | |
| SCHEMBL8025473 | 0.70 | HSP90AA1 (0.37) | MAPTALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL8032092 | 0.70 | ALDH1A1 (0.44) | POLBMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL8035585 | 0.69 | HSP90AA1 (0.41) | MAPTALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL8039016 | 0.69 | HTT (0.42) | ALDH1A1KDM4ELMNAHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |