Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.35 |
| ▸ | UBE2M | P61081 | 5/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045085 | 0.90 | POLB (0.43) | HTTLMNAPOLBMAPTNPSR1 | |
| SCHEMBL8043865 | 0.86 | RAB9A (0.42) | HTTLMNAMAPTNPSR1DCUN1D1 | |
| SCHEMBL8044430 | 0.85 | CTSS (0.34) | HTTLMNAPOLBMAPTDCUN1D1 | |
| SCHEMBL8043192 | 0.83 | ALDH1A1 (0.35) | HTTLMNAPOLBMAPTDCUN1D1 | |
| SCHEMBL8045490 | 0.83 | EIF4E (0.36) | HTTPOLBMAPTNPSR1EIF4E | |
| SCHEMBL8032734 | 0.82 | ALDH1A1 (0.37) | HTTPOLBMAPTNPSR1EIF4E | |
| SCHEMBL8042146 | 0.82 | KDM4E (0.42) | HTTLMNAMAPTNPSR1SLC6A2 | |
| SCHEMBL8048771 | 0.81 | MAPT (0.37) | LMNAMAPTEIF4EALDH1A1KDM4E | |
| SCHEMBL8043200 | 0.81 | ALDH1A1 (0.43) | HTTLMNAPOLBMAPTNPSR1 | |
| SCHEMBL8047810 | 0.80 | CYP2C9 (0.37) | HTTLMNAMAPTNPSR1DCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |