Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033189 | 0.91 | RAB9A (0.38) | EIF4ELTA4HALDH1A1KMT2AAR | |
| SCHEMBL8048789 | 0.87 | HTR1A (0.45) | LTA4HALDH1A1KMT2AARKDM4E | |
| SCHEMBL8050993 | 0.84 | CTSS (0.36) | EIF4ELTA4HARHTR1AHTR2A | |
| SCHEMBL8050819 | 0.83 | F2RL3 (0.36) | EIF4ELTA4HALDH1A1KMT2AAR | |
| SCHEMBL8037022 | 0.83 | HTT (0.38) | EIF4ELTA4HALDH1A1KMT2AKDM4E | |
| SCHEMBL8050186 | 0.82 | ATP4A (0.35) | ALDH1A1KMT2AARRAB9AMAPT | |
| SCHEMBL8046628 | 0.82 | AR (0.40) | LTA4HKMT2AARKDM4EMEN1 | |
| SCHEMBL8048213 | 0.81 | XPO1 (0.40) | EIF4EALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL8032747 | 0.80 | F2RL3 (0.37) | EIF4EALDH1A1KMT2AARKDM4E | |
| SCHEMBL8042050 | 0.79 | LMNA (0.42) | ALDH1A1KMT2AMEN1HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |