Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.33 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033842 | 0.94 | RAB9A (0.42) | SMOPOLBRAB9AS1PR1PDE4D | |
| SCHEMBL8028301 | 0.87 | APP (0.39) | APPRAB9AS1PR1LRRK2TMPRSS4 | |
| SCHEMBL8038215 | 0.83 | S1PR1 (0.40) | APPRAB9AS1PR1LRRK2TMPRSS4 | |
| SCHEMBL8041698 | 0.81 | CYP1A2 (0.41) | APPS1PR1LRRK2TMPRSS4KDM4E | |
| SCHEMBL8041701 | 0.81 | APP (0.38) | APPS1PR1LRRK2LMNAMAPT | |
| SCHEMBL8040252 | 0.80 | ALDH1A1 (0.41) | POLBS1PR1LRRK2KDM4ELMNA | |
| SCHEMBL8035618 | 0.80 | APP (0.44) | SMOAPPRAB9AKDM4EHPGD | |
| SCHEMBL8040276 | 0.80 | SMO (0.34) | SMOAPPPOLBRAB9APDE4D | |
| SCHEMBL8037366 | 0.80 | S1PR1 (0.41) | APPS1PR1KDM4ELMNACYP3A4 | |
| SCHEMBL8037831 | 0.77 | ALDH1A1 (0.48) | POLBRAB9ALMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |