Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389785 | 0.64 | ALDH1A1 (0.51) | DRD2ESR2DRD4ALDH1A1LMNA | |
| SCHEMBL8034901 | 0.63 | ALDH1A1 (0.37) | ESR2ALDH1A1LMNAHSD17B10MAOA | |
| SCHEMBL8038664 | 0.63 | DRD2 (0.33) | DRD2ESR2DRD4ALDH1A1LMNA | |
| SCHEMBL11394354 | 0.61 | CYP3A4 (0.39) | DRD2ESR2DRD4ALDH1A1HSD17B10 | |
| SCHEMBL8034883 | 0.61 | BCL2L1 (0.38) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL577820 | 0.61 | DRD2 (0.41) | DRD2ESR2DRD4HSD17B10HSP90AA1 | |
| SCHEMBL5422777 | 0.61 | DRD2 (0.39) | DRD2DRD4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9119395 | 0.59 | MAOA (0.43) | DRD2ESR2DRD4DRD3MAOA | |
| SCHEMBL19268932 | 0.58 | OPRK1 (0.44) | DRD2ESR2DRD4ALDH1A1LMNA | |
| SCHEMBL12807492 | 0.58 | KDM4E (0.39) | DRD2DRD4ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661039-B1 | Oxidative hair dyeing method, composition and kit utilizing hydroxyl substituted benzothiazines | BRISTOL MYERS SQUIBB CO (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0661039-A1 | Oxidative hair dyeing method, composition and kit utilizing hydroxyl substituted benzothiazines | Bristol-Myers Squibb Company (US) | 1995-07-05 | — | — | EP | disclosed |
| US-5374288-A | Oxidative hair dyeing method, composition, and kit utilizing hydroxyl substituted benzothiazines | CLAIROL INCORPORATED (US) | 1994-12-20 | — | — | US | disclosed |