Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 6/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3438836 | 0.87 | SMN1; SMN2 (0.54) | PRSS1PRSS2PRSS3ALDH1A1HTT | |
| SCHEMBL1992569 | 0.83 | SMN1; SMN2 (0.42) | PRSS1PRSS2PRSS3ALDH1A1HTT | |
| SCHEMBL2910990 | 0.82 | HDAC4 (0.51) | MAOBALDH1A1HPGD | |
| SCHEMBL8051490 | 0.81 | POLB (0.42) | PRSS1PRSS2PRSS3ALDH1A1HTT | |
| SCHEMBL29941779 | 0.78 | PRSS1 (0.49) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL1671484 | 0.78 | PRSS1 (0.49) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL3438833 | 0.78 | PARP1 (0.44) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL14879763 | 0.77 | PRSS1 (0.41) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL15772720 | 0.76 | LMNA (0.41) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL14898222 | 0.74 | PRSS1 (0.38) | PRSS1PRSS2PRSS3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11970448-B2 | Monomers capable of dimerizing in an aqueous solution, and methods of using same | CORNELL UNIVERSITY (US) | 2024-04-30 | — | — | US | disclosed |
| US-10912786-B2 | Silyl monomers capable of multimerizing in an aqueous solution, and methods of using same | CORNELL UNIVERSITY (US) | 2021-02-09 | — | — | US | disclosed |
| US-20200354319-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | UNIV CORNELL (US) | 2020-11-12 | — | — | US | disclosed |
| EP-2693883-B1 | SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | UNIV CORNELL (US) | 2018-12-26 | — | — | EP | disclosed |
| US-20170080001-A1 | SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CORNELL UNIVERSITY | 2017-03-23 | — | — | US | disclosed |
| US-20140194383-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CORNELL UNIVERSITY (US) | 2014-07-10 | — | — | US | disclosed |
| US-20140163229-A1 | SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CORNELL UNIVERSITY (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140161729-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2014-06-12 | — | — | US | disclosed |
| EP-2694707-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | Cornell University (US) | 2014-02-12 | — | — | EP | disclosed |
| WO-2013058824-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CORNELL UNIVERSITY (US) | 2013-04-25 | — | — | WO | disclosed |
| WO-2012154213-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
| WO-2009067202-A1 | SPIROPIPERIDINES FOR USE AS TRYPTASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11970448-B2 | Monomers capable of dimerizing in an aqueous solution, and methods of using same | CALCOCO2, MDN1, MBNL1 | PRSS1 2733/4885PRSS2 2788/4885PRSS3 3354/4885 |
| US-10912786-B2 | Silyl monomers capable of multimerizing in an aqueous solution, and methods of using same | STIM1, STAMBP, ILK | PRSS1 1838/4885PRSS2 2294/4885PRSS3 2821/4885 |
| US-20140161729-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | TNFSF11, CD14, TNFRSF1A | PRSS1 4125/4885PRSS2 4301/4885PRSS3 4028/4885 |
| US-20200354319-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CALCOCO2, MDN1, MBNL1 | PRSS1 2733/4885PRSS2 2788/4885PRSS3 3354/4885 |
| US-20140194383-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CALCOCO2, MDN1, MBNL1 | PRSS1 2733/4885PRSS2 2788/4885PRSS3 3354/4885 |
| US-20170080001-A1 | SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | STIM1, STAMBP, ILK | PRSS1 1838/4885PRSS2 2294/4885PRSS3 2821/4885 |
| US-20140163229-A1 | SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | STIM1, STAMBP, ILK | PRSS1 1838/4885PRSS2 2294/4885PRSS3 2821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.