Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034762 | 0.84 | HPGD (0.43) | SIGMAR1TMEM97RAB9AHPGDHDAC3 | |
| SCHEMBL14679116 | 0.82 | L3MBTL1 (0.53) | SIGMAR1TMEM97RAB9AHPGDMEN1 | |
| SCHEMBL7719747 | 0.82 | EPHX2 (0.52) | SIGMAR1TMEM97EPHX2PPARARAB9A | |
| SCHEMBL15382631 | 0.81 | SIGMAR1 (0.69) | SIGMAR1TMEM97EPHX2GFERRAB9A | |
| SCHEMBL28223322 | 0.81 | MGLL (0.53) | SIGMAR1TMEM97EPHX2RAB9ANAMPT | |
| SCHEMBL21998217 | 0.79 | PPARA (0.41) | EPHX2PPARARAB9ACCNCCDK8 | |
| SCHEMBL23099545 | 0.78 | FPR3 (0.41) | SIGMAR1TMEM97RAB9AHPGDMEN1 | |
| SCHEMBL31245830 | 0.78 | CA14 (0.41) | SIGMAR1TMEM97HPGDMEN1KMT2A | |
| SCHEMBL14679115 | 0.78 | NPC1 (0.51) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL31059259 | 0.77 | ALDH1A1 (0.43) | SIGMAR1TMEM97EPHX2PPARAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063791-A | N-benzenesulfonyl-L-proline derivatives, method for preparing and therapeutic use | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-05-16 | — | — | US | disclosed |