Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.82 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.82 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eflucimibe SCHEMBL29427708 | 0.91 | SOAT2 (1.00) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| Eflucimibe SCHEMBL668294 | 0.91 | SOAT2 (1.00) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| Eflucimibe SCHEMBL668292 | 0.91 | SOAT2 (1.00) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| SCHEMBL8041413 | 0.85 | SOAT1 (0.54) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| SCHEMBL8080785 | 0.84 | SOAT2 (0.62) | SOAT2ACAT1SOAT1ALDH1A1LMNA | |
| SCHEMBL5900910 | 0.81 | SOAT2 (0.80) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| SCHEMBL5900907 | 0.81 | SOAT2 (0.80) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| SCHEMBL8417193 | 0.81 | SOAT2 (0.73) | SOAT2ACAT1SOAT1ALDH1A1LMNA | |
| SCHEMBL8079670 | 0.80 | SOAT1 (0.79) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| SCHEMBL8416087 | 0.80 | SOAT2 (0.78) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874812-B1 | NOVEL 2,3,5-TRIMETHYL-4-HYDROXY ANILIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | PF MEDICAMENT (FR) | 2000-04-05 | — | — | EP | claimed |