Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.80 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.80 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5900910 | 1.00 | SOAT2 (0.80) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| Eflucimibe SCHEMBL668292 | 0.89 | SOAT2 (1.00) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| Eflucimibe SCHEMBL29427708 | 0.89 | SOAT2 (1.00) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| Eflucimibe SCHEMBL668294 | 0.89 | SOAT2 (1.00) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| SCHEMBL13269963 | 0.82 | SOAT2 (0.76) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| Eflucimibe SCHEMBL8041449 | 0.81 | SOAT2 (0.82) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| SCHEMBL5901323 | 0.80 | SOAT2 (0.52) | SOAT2ACAT1SOAT1MAPTMEN1 | |
| SCHEMBL5901319 | 0.80 | SOAT2 (0.52) | SOAT2ACAT1SOAT1MAPTMEN1 | |
| SCHEMBL8079670 | 0.78 | SOAT1 (0.79) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 | |
| SCHEMBL13249165 | 0.78 | SOAT2 (0.73) | SOAT2ACAT1SOAT1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060135785-A1 | Alpha-phenyl acetanilide derivatives having an acat inhibiting activity and the therapeutic application thereof | PIERRE FABRE MEDICAMENT (FR) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135785-A1 | Alpha-phenyl acetanilide derivatives having an acat inhibiting activity and the therapeutic application thereof | ACAT2, ACAT1, LCAT | SOAT2 109/4885ACAT1 2/4885SOAT1 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.