Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033974 | 0.93 | LMNA (0.49) | RAB9ANPC1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8046726 | 0.89 | RAB9A (0.41) | RAB9ANPC1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8033238 | 0.87 | RAB9A (0.52) | RAB9ANPC1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8050800 | 0.84 | HTR1A (0.49) | RAB9ANPC1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8043767 | 0.84 | KDM4E (0.49) | RAB9ANPC1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8048106 | 0.83 | KDM4E (0.56) | RAB9ANPC1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8043994 | 0.82 | ALDH1A1 (0.53) | RAB9ANPC1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8043113 | 0.82 | RAB9A (0.48) | RAB9ANPC1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8042512 | 0.81 | RAB9A (0.50) | RAB9ANPC1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8050920 | 0.81 | RAB9A (0.39) | RAB9ANPC1TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |