Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | EIF4E | P06730 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051863 | 0.86 | MAPT (0.35) | MAPTMEN1KMT2ATDP1ALOX5 | |
| SCHEMBL8033982 | 0.83 | KDM4E (0.50) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8046511 | 0.81 | HTT (0.45) | MAPTMEN1KMT2ATDP1ALOX5 | |
| SCHEMBL8043093 | 0.81 | SMN1; SMN2 (0.38) | MAPTTDP1ALOX5F2RL3EIF4E | |
| SCHEMBL8032747 | 0.79 | F2RL3 (0.37) | MAPTMEN1KMT2ATDP1ALOX5 | |
| SCHEMBL8033951 | 0.78 | HTR1A (0.46) | MAPTMEN1KMT2ATDP1AR | |
| SCHEMBL8045256 | 0.76 | MAPT (0.35) | MAPTALOX5F2RL3EIF4EAR | |
| SCHEMBL8048290 | 0.76 | MAPT (0.35) | MAPTMEN1KMT2AALOX5F2RL3 | |
| SCHEMBL8042665 | 0.76 | MAPT (0.41) | MAPTKMT2AALOX5F2RL3PKM | |
| SCHEMBL8043006 | 0.76 | RAB9A (0.43) | MAPTMEN1KMT2ATDP1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |