Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033951 | 0.86 | HTR1A (0.46) | RAB9ANPC1MAPTLMNAMEN1 | |
| SCHEMBL8044780 | 0.84 | RAB9A (0.41) | RAB9ANPC1MAPTLMNAMEN1 | |
| SCHEMBL8048096 | 0.82 | MAPT (0.55) | RAB9ANPC1MAPTLMNAMEN1 | |
| SCHEMBL8050040 | 0.79 | HTT (0.51) | RAB9ANPC1MAPTLMNAMEN1 | |
| SCHEMBL8046692 | 0.79 | ABL1 (0.44) | RAB9ANPC1MAPTLMNAMEN1 | |
| SCHEMBL8033890 | 0.77 | RAB9A (0.46) | RAB9ANPC1MAPTLMNAMEN1 | |
| SCHEMBL8042227 | 0.76 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8044478 | 0.75 | MEN1 (0.40) | RAB9ANPC1MAPTLMNAMEN1 | |
| SCHEMBL8044646 | 0.74 | ALDH1A1 (0.52) | RAB9ANPC1MAPTLMNAMEN1 | |
| SCHEMBL8041816 | 0.74 | RAB9A (0.47) | RAB9ANPC1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |