Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033607 | 0.69 | KDM4E (0.36) | — | |
| SCHEMBL4123024 | 0.64 | ALDH1A1 (0.36) | HTR2AHTR2CHTR7 | |
| SCHEMBL8053716 | 0.61 | EED (0.32) | — | |
| SCHEMBL8043252 | 0.61 | KDM4E (0.36) | — | |
| SCHEMBL4139405 | 0.60 | KDM4E (0.34) | HTR2AHTR2CHTR7 | |
| SCHEMBL8042659 | 0.60 | KDM4E (0.37) | — | |
| SCHEMBL8031553 | 0.60 | KDM4E (0.34) | — | |
| SCHEMBL4132580 | 0.59 | KDM4E (0.35) | — | |
| SCHEMBL8045132 | 0.55 | KDM4E (0.41) | — | |
| SCHEMBL12359572 | 0.54 | SIGMAR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071707-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2009-06-11 | — | — | WO | disclosed |