Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM6A | O15550 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13272097 | 1.00 | PTGS2 (0.40) | PTGS2KDM6BKDM6AMAPTHSD17B10 | |
| SCHEMBL804301 | 0.92 | KDM6B (0.50) | PTGS2KDM6BKDM6AMAPTHSD17B10 | |
| SCHEMBL804636 | 0.77 | CNR2 (0.41) | PTGS2KDM6BKDM6AMAPTHSD17B10 | |
| SCHEMBL28942264 | 0.72 | MMP2 (0.46) | — | |
| SCHEMBL536401 | 0.72 | MMP2 (0.46) | — | |
| SCHEMBL1994589 | 0.72 | PDK2 (0.41) | — | |
| SCHEMBL5906495 | 0.72 | NPC1 (0.37) | MAPTHSD17B10ALDH1A1TP53KMT2A | |
| SCHEMBL25362290 | 0.72 | MAOA (0.39) | ALDH1A1NPSR1HPGDNPC1CHRNB4 | |
| SCHEMBL17197380 | 0.71 | MGLL (0.44) | PTGS2MAPTHSD17B10ALDH1A1TP53 | |
| SCHEMBL27964989 | 0.71 | MGLL (0.44) | PTGS2MAPTHSD17B10ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070378-A1 | LANTHANIDE ION COMPLEXES AND IMAGING METHOD | THE UNIVERSITY OF AKRON (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120070378-A1 | LANTHANIDE ION COMPLEXES AND IMAGING METHOD | THE UNIVERSITY OF AKRON (US) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070378-A1 | LANTHANIDE ION COMPLEXES AND IMAGING METHOD | INSR, KCNH3, CA9 | PTGS2 3584/4885KDM6B 4367/4885KDM6A 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.