Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 2/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044748 | 0.89 | TP53 (0.42) | KMT2AMEN1HTTRAB9AHSD17B10 | |
| SCHEMBL8044812 | 0.83 | ALDH1A1 (0.52) | KMT2AMEN1UBE2MDCUN1D1HTT | |
| SCHEMBL8046536 | 0.81 | KDM4E (0.33) | HTTMAPTKDM4EAR | |
| SCHEMBL8044696 | 0.81 | HTT (0.40) | KMT2AMEN1UBE2MDCUN1D1HTT | |
| SCHEMBL8042172 | 0.81 | ALDH1A1 (0.38) | KMT2AMEN1UBE2MDCUN1D1HTT | |
| SCHEMBL8043071 | 0.79 | TP53 (0.35) | KMT2AMEN1HTTRAB9AHSD17B10 | |
| SCHEMBL8046744 | 0.79 | ALDH1A1 (0.48) | KMT2AMEN1HTTRAB9AHSD17B10 | |
| SCHEMBL8045872 | 0.78 | FBP1 (0.40) | KMT2AMEN1HTTHSD17B10HTR7 | |
| SCHEMBL8044443 | 0.78 | ALDH1A1 (0.49) | KMT2AMEN1UBE2MDCUN1D1HTT | |
| SCHEMBL8048673 | 0.78 | MEN1 (0.40) | KMT2AMEN1HTTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |