Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050863 | 0.82 | ALOX5 (0.35) | KDM4EHTTPAX8PIP4K2CAR | |
| SCHEMBL8043970 | 0.81 | KMT2A (0.43) | KDM4EHTTARMAPT | |
| SCHEMBL8044497 | 0.81 | HTT (0.33) | KDM4EHTTPAX8PIP4K2CAR | |
| SCHEMBL8043200 | 0.81 | ALDH1A1 (0.43) | KDM4EHTTMAPT | |
| SCHEMBL8044748 | 0.80 | TP53 (0.42) | KDM4EHTTPIP4K2CARMAPT | |
| SCHEMBL8033936 | 0.79 | ALDH1A1 (0.42) | KDM4EHTTPAX8PIP4K2CAR | |
| SCHEMBL8043905 | 0.79 | KDM4E (0.37) | KDM4EHTTPAX8PIP4K2CMAPT | |
| SCHEMBL8046511 | 0.79 | HTT (0.45) | HTTPAX8PIP4K2CMAPTALOX5 | |
| SCHEMBL8043675 | 0.79 | KIT (0.39) | KDM4EHTT | |
| SCHEMBL8050841 | 0.78 | ALDH1A1 (0.37) | KDM4EHTTPAX8PIP4K2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |