Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038297 | 0.90 | LMNA (0.55) | MAPTTDP1LMNANPSR1ALDH1A1 | |
| SCHEMBL8039699 | 0.83 | TSHR (0.58) | MAPTTDP1LMNANPSR1ALDH1A1 | |
| SCHEMBL8044216 | 0.77 | ALDH1A1 (0.57) | MAPTLMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2291513 | 0.76 | KDM4E (0.69) | MAPTLMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10833856 | 0.75 | SIRT2 (0.74) | MAPTLMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8027769 | 0.74 | ALDH1A1 (0.53) | MAPTTDP1LMNANPSR1ALDH1A1 | |
| SCHEMBL6338190 | 0.73 | KDM4E (0.66) | MAPTLMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6349020 | 0.73 | ALDH1A1 (0.60) | MAPTLMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4735942 | 0.72 | HTT (0.52) | MAPTTDP1LMNANPSR1ALDH1A1 | |
| SCHEMBL8037897 | 0.72 | CTSV (0.52) | LMNASMN1; SMN2L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |