Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043957 | 0.88 | MAPK8 (0.33) | MAPK8MAPK9MAPK10 | |
| SCHEMBL8043004 | 0.85 | MAPK8 (0.39) | MAPK8MAPK9MAPK10 | |
| SCHEMBL8044324 | 0.84 | ALDH1A1 (0.37) | MAPK8MAPK9MAPK10 | |
| SCHEMBL8043915 | 0.81 | MAPK8 (0.37) | MAPK8MAPK9MAPK10 | |
| SCHEMBL8043927 | 0.80 | ATM (0.47) | — | |
| SCHEMBL8044476 | 0.79 | MAPK8 (0.33) | MAPK8MAPK9MAPK10 | |
| SCHEMBL8044736 | 0.78 | RXRA (0.40) | MAPK8MAPK9MAPK10 | |
| SCHEMBL8034054 | 0.78 | F2 (0.44) | MAPK8MAPK9MAPK10 | |
| SCHEMBL8051775 | 0.78 | POLB (0.40) | MAPK8MAPK9MAPK10 | |
| SCHEMBL8032889 | 0.77 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |