Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046664 | 0.83 | CA12 (0.42) | CA12CA1CA2CA9HTT | |
| SCHEMBL8041836 | 0.81 | ALDH1A1 (0.42) | HTTUSP2 | |
| SCHEMBL8048331 | 0.80 | ALDH1A1 (0.33) | USP2 | |
| SCHEMBL8051237 | 0.79 | SMN1; SMN2 (0.30) | USP2TSHR | |
| SCHEMBL8045938 | 0.79 | HSD17B10 (0.40) | HTT | |
| SCHEMBL8042077 | 0.78 | ALDH1A1 (0.39) | CA12CA1CA2CA9HTT | |
| SCHEMBL8050732 | 0.77 | RXRA (0.43) | USP2TSHR | |
| SCHEMBL8048309 | 0.77 | ALDH1A1 (0.52) | HTTTSHR | |
| SCHEMBL8033250 | 0.77 | HTT (0.41) | HTTUSP2TSHR | |
| SCHEMBL8050401 | 0.77 | KMT2A (0.36) | HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |