Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045938 | 0.90 | HSD17B10 (0.40) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8033250 | 0.88 | HTT (0.41) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL8050401 | 0.85 | KMT2A (0.36) | ALDH1A1NPC1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL8046664 | 0.84 | CA12 (0.42) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8047435 | 0.83 | LMNA (0.33) | KMT2AHTTLMNA | |
| SCHEMBL8050069 | 0.83 | ALDH1A1 (0.45) | ALDH1A1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8052603 | 0.82 | DCUN1D1 (0.37) | KMT2AHTTLMNA | |
| SCHEMBL8714264 | 0.82 | CYP2C19 (0.43) | ALDH1A1KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL8044868 | 0.81 | ALDH1A1 (0.38) | ALDH1A1NPC1RAB9APOLBKMT2A | |
| SCHEMBL8044376 | 0.81 | CA12 (0.33) | USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |