Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 12/20 | 0.42 |
| ▸ | PIP4K2C | Q8TBX8 | 10/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045938 | 0.84 | HSD17B10 (0.40) | HTTALDH1A1LMNAMEN1TP53 | |
| SCHEMBL8041836 | 0.84 | ALDH1A1 (0.42) | HTTALDH1A1LMNAMEN1TP53 | |
| SCHEMBL8044376 | 0.83 | CA12 (0.33) | CA12CA1CA2CA9HTT | |
| SCHEMBL8048331 | 0.83 | ALDH1A1 (0.33) | ALDH1A1MEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL8033250 | 0.82 | HTT (0.41) | HTTALDH1A1LMNAMEN1POLB | |
| SCHEMBL8047435 | 0.80 | LMNA (0.33) | HTTLMNAKMT2A | |
| SCHEMBL8048309 | 0.80 | ALDH1A1 (0.52) | HTTALDH1A1LMNAMEN1TP53 | |
| SCHEMBL8050401 | 0.80 | KMT2A (0.36) | HTTALDH1A1LMNATP53TSHR | |
| SCHEMBL8714264 | 0.80 | CYP2C19 (0.43) | HTTALDH1A1LMNAMEN1TP53 | |
| SCHEMBL8052603 | 0.80 | DCUN1D1 (0.37) | HTTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |