Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 2/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050069 | 0.89 | ALDH1A1 (0.45) | ALDH1A1HPGDKMT2AMEN1HTT | |
| SCHEMBL8045938 | 0.84 | HSD17B10 (0.40) | ALDH1A1KMT2AMEN1HTTGAA | |
| SCHEMBL8033250 | 0.82 | HTT (0.41) | ALDH1A1POLBHPGDKMT2AMEN1 | |
| SCHEMBL8033672 | 0.82 | NPSR1 (0.39) | ALDH1A1KMT2AMEN1SLC1A2SLC1A3 | |
| SCHEMBL8050397 | 0.81 | ALDH1A1 (0.40) | ALDH1A1POLBHPGDKMT2AMEN1 | |
| SCHEMBL8041836 | 0.81 | ALDH1A1 (0.42) | ALDH1A1POLBKMT2AMEN1HTT | |
| SCHEMBL8047435 | 0.80 | LMNA (0.33) | KMT2AHTTLMNA | |
| SCHEMBL8050401 | 0.80 | KMT2A (0.36) | ALDH1A1HPGDKMT2AHTTTSHR | |
| SCHEMBL8048309 | 0.80 | ALDH1A1 (0.52) | ALDH1A1POLBHPGDKMT2AMEN1 | |
| SCHEMBL8051088 | 0.80 | NPC1 (0.45) | ALDH1A1KMT2AMEN1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |