Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045080 | 0.89 | LMNA (0.31) | LMNAKMT2A | |
| SCHEMBL8033250 | 0.88 | HTT (0.41) | LMNAKMT2AHTT | |
| SCHEMBL8032986 | 0.86 | RXRA (0.34) | LMNAKMT2AHTT | |
| SCHEMBL8045938 | 0.86 | HSD17B10 (0.40) | LMNAKMT2AHTT | |
| SCHEMBL8714264 | 0.85 | CYP2C19 (0.43) | LMNAKMT2AHTT | |
| SCHEMBL8052603 | 0.85 | DCUN1D1 (0.37) | LMNAKMT2AHTT | |
| SCHEMBL8050061 | 0.85 | NPC1 (0.45) | LMNAKMT2AHTT | |
| SCHEMBL8041836 | 0.83 | ALDH1A1 (0.42) | LMNAKMT2AHTT | |
| SCHEMBL8044130 | 0.82 | NPSR1 (0.33) | LMNAKMT2AHTT | |
| SCHEMBL8046664 | 0.80 | CA12 (0.42) | LMNAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |