Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CLK1 | P49759 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033846 | 0.82 | PDK1 (0.52) | ALDH1A1LMNAHTTTSHRUSP2 | |
| SCHEMBL8043823 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAHPGDTSHRUSP2 | |
| SCHEMBL8033856 | 0.81 | PKM (0.46) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL8033848 | 0.80 | TXN (0.50) | ALDH1A1LMNAHPGDHTTTSHR | |
| SCHEMBL8043670 | 0.79 | PKM (0.44) | ALDH1A1LMNAHPGDHTTCLK1 | |
| SCHEMBL8047478 | 0.79 | PKM (0.44) | ALDH1A1LMNAHPGDHTTCLK1 | |
| SCHEMBL8049026 | 0.79 | PKM (0.46) | ALDH1A1LMNAHPGDHTTCLK1 | |
| SCHEMBL8052304 | 0.77 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDHTTCLK1 | |
| SCHEMBL8042747 | 0.77 | PKM (0.42) | ALDH1A1LMNAHPGDHTTCLK1 | |
| SCHEMBL8042322 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDHTTCLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |