Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033073 | 0.82 | RAB9A (0.36) | LMNAKMT2ATP53GAARAB9A | |
| SCHEMBL8047435 | 0.82 | LMNA (0.33) | LMNAKMT2AHTT | |
| SCHEMBL8043030 | 0.82 | HTT (0.42) | NPSR1LMNAKMT2AALOX15GAA | |
| SCHEMBL8045080 | 0.80 | LMNA (0.31) | LMNAKMT2A | |
| SCHEMBL8045352 | 0.79 | ALOX15 (0.41) | NPSR1LMNAKMT2AALOX15RAB9A | |
| SCHEMBL8717421 | 0.79 | HTR7 (0.36) | NPSR1KDM1A | |
| SCHEMBL8045829 | 0.79 | HTR7 (0.47) | NPSR1LMNAKMT2AKDM1A | |
| SCHEMBL8710280 | 0.79 | CYP2C9 (0.44) | NPSR1LMNAKMT2AALOX15TP53 | |
| SCHEMBL8032986 | 0.78 | RXRA (0.34) | LMNAKMT2ATP53GAASMN1; SMN2 | |
| SCHEMBL8041849 | 0.77 | RAB9A (0.38) | LMNAKMT2ATP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |