Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | UBE2M | P61081 | 3/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042823 | 0.92 | ALDH1A1 (0.44) | KMT2ASMN1; SMN2LMNARAB9AALDH1A1 | |
| SCHEMBL8032361 | 0.88 | ALDH1A1 (0.47) | KMT2ASMN1; SMN2LMNARAB9AALDH1A1 | |
| SCHEMBL8043987 | 0.83 | ALDH1A1 (0.45) | KMT2ASMN1; SMN2LMNARAB9AHSD17B10 | |
| SCHEMBL8042045 | 0.83 | UBE2M (0.46) | UBE2MDCUN1D1 | |
| SCHEMBL8033559 | 0.82 | LMNA (0.47) | KMT2ALMNARAB9AHSD17B10ALDH1A1 | |
| SCHEMBL8042838 | 0.80 | SMN1; SMN2 (0.50) | KMT2ASMN1; SMN2LMNARAB9AHSD17B10 | |
| SCHEMBL8043746 | 0.80 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2LMNARAB9AHSD17B10 | |
| SCHEMBL8034187 | 0.79 | HTR1A (0.44) | KMT2ASMN1; SMN2LMNARAB9AALOX15 | |
| SCHEMBL8033073 | 0.79 | RAB9A (0.36) | KMT2ASMN1; SMN2LMNARAB9AALDH1A1 | |
| SCHEMBL8047351 | 0.79 | KMT2A (0.47) | KMT2ALMNARAB9AALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |