Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 16/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046056 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HPGDTDP1KDM4EALOX15 | |
| SCHEMBL8044734 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HPGDTDP1KDM4EALOX15 | |
| SCHEMBL8046511 | 0.79 | HTT (0.45) | ALDH1A1TDP1HSD17B10MEN1KMT2A | |
| SCHEMBL8045256 | 0.77 | MAPT (0.35) | ALDH1A1KDM4EL3MBTL1HTTMAPT | |
| SCHEMBL8048290 | 0.77 | MAPT (0.35) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL8032734 | 0.76 | ALDH1A1 (0.37) | ALDH1A1KDM4EL3MBTL1HTTMAPT | |
| SCHEMBL8051935 | 0.76 | GAA (0.39) | ALDH1A1HPGDTDP1KDM4EALOX15 | |
| SCHEMBL8046719 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HPGDTDP1KDM4EALOX15 | |
| SCHEMBL8043200 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HPGDTDP1KDM4EHSD17B10 | |
| SCHEMBL8044430 | 0.74 | CTSS (0.34) | ALDH1A1KDM4EALOX15HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |