Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044438 | 0.86 | ALDH1A1 (0.41) | KMT2AKEAP1ALDH1A1HTTNPSR1 | |
| SCHEMBL8052232 | 0.85 | ALDH1A1 (0.43) | MEN1KMT2AKEAP1ALDH1A1HTT | |
| SCHEMBL8046773 | 0.84 | PKM (0.41) | MEN1KMT2AALDH1A1HTTNPSR1 | |
| SCHEMBL8043961 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1HTTNPSR1 | |
| SCHEMBL8050394 | 0.80 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1HTTNPSR1 | |
| SCHEMBL8043221 | 0.79 | PDK1 (0.44) | NPC1MEN1KMT2AKEAP1ALDH1A1 | |
| SCHEMBL8043682 | 0.79 | HTT (0.50) | NPC1RAB9AKMT2AALDH1A1HTT | |
| SCHEMBL8034272 | 0.79 | ALDH1A1 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL8044246 | 0.79 | ALDH1A1 (0.39) | KMT2AALDH1A1HTTNPSR1MAPT | |
| SCHEMBL8032480 | 0.76 | PKM (0.38) | MEN1KMT2AALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |