Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048583 | 0.93 | ALDH1A1 (0.45) | ALDH1A1RAB9ATSHRLMNAP2RX7 | |
| SCHEMBL8042146 | 0.90 | KDM4E (0.42) | RAB9ALMNANR1I3ALOX5PLAU | |
| SCHEMBL8713674 | 0.87 | LMNA (0.40) | ALDH1A1RAB9ATSHRLMNANR1I3 | |
| SCHEMBL8045832 | 0.86 | LMNA (0.42) | ALDH1A1RAB9ATSHRLMNAKMT2A | |
| SCHEMBL8043207 | 0.85 | MAPT (0.44) | ALDH1A1RAB9ATSHRLMNAKMT2A | |
| SCHEMBL8041897 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNAALOX5KMT2A | |
| SCHEMBL8044036 | 0.83 | KMT2A (0.44) | ALDH1A1RAB9ALMNAKMT2AMAPK1 | |
| SCHEMBL8044646 | 0.83 | ALDH1A1 (0.52) | ALDH1A1RAB9ALMNAKMT2AMAPK1 | |
| SCHEMBL8045085 | 0.82 | POLB (0.43) | ALDH1A1RAB9ATSHRLMNAP2RX7 | |
| SCHEMBL8720492 | 0.81 | RAB9A (0.41) | ALDH1A1RAB9ALMNAALOX5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |